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- Title
Clinical Spectrum of Skin Manifestations of Lyme Borreliosis in 204 Children in Austria.
- Authors
GLATZ, Martin; RESINGER, Astrid; SEMMELWEIS, Kristina; AMBROS-RUDOLPH, Christina M.; MÜLLEGGER, Robert R.
- Abstract
The spectrum of skin manifestations of Lyme borreliosis in children is not well characterized. We conducted a retrospective study to analyze the clinical characteristics, seroreactivity to Borrelia burgdorferi sensu lato, and outcome after treatment in 204 children with skin manifestations of Lyme borreliosis seen in 1996-2011. Solitary erythema migrans was the most common manifestation (44.6%), followed by erythema migrans with multiple lesions (27%), borrelial lymphocytoma (21.6%), and acrodermatitis chronica atrophicans (0.9%). A collision lesion of a primary borrelial lymphocytoma and a surrounding secondary erythema migrans was diagnosed in 5.9% of children. Rate of seroreactivity to B. burgdorferi sensu lato was lower in solitary erythema migrans compared to other diagnosis groups. Amoxicillin or phenoxymethylpenicillin led to complete resolution of erythema migrans within a median of 6 (solitary) and 14 days (multiple lesions), respectively, and of borrelia lymphocytoma within a median of 56 days. In conclusion, erythema migrans with multiple lesions and borrelial lymphocytoma appear to be more frequent in children than in adults, whereas acrodermatitis chronica atrophicans is a rarity in childhood. The outcome after antibiotic therapy was excellent in children, and appears to be better than in adults.
- Subjects
LYME disease; SKIN diseases; TICK-borne diseases; BORRELIA diseases; PEDIATRIC dermatology
- Publication
Acta Dermato-Venereologica, 2015, Vol 95, Issue 5, p565
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-2000