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- Title
Effectiveness of non-pharmacological therapies for chronic pain in people with autoimmune diseases in Africa: A protocol for a systematic review and meta-analysis.
- Authors
Gebremeskel, Gebreamlak Gebremedhn; Haile, Teklehaimanot Gereziher; Gebrewahd, Gebremeskel Tukue; Hailay, Abrha; Aberhe, Woldu; Mebrahtom, Guesh; Zereabruk, Kidane; Negash, Assefa Iyasu; Gebrekidan, Hailemikael; Tadesse, Degena Bahrey
- Abstract
Background: Autoimmune diseases affect 5–10% of the global population and cause chronic pain and impaired functionality. Chronic pain management involves pharmacological and non-pharmacological interventions, with non-pharmacological options gaining attention as safe, effective, and cost-effective alternatives. However, further research is needed to determine the effectiveness of these therapies in African patients with autoimmune diseases, as existing evidence varies. Methods: This review protocol has been registered in the International Prospective Register of Systematic Reviews (PROSPERO, CRD42023449896). Electronic databases (PubMed, Africa Index Medicus, Cochrane Library, CINAHL, PsycINFO, and Web of Science) will be used for searching published articles. The study will use R for data synthesis, employing a random-effects meta-analysis approach to calculate pooled effect sizes, assess heterogeneity using the I2 statistic, and evaluate publication bias. In conclusion, this protocol aims to fill the knowledge gap on non-pharmacological therapies for chronic pain in patients with autoimmune diseases in Africa. It will potentially enhance evidence-based decision-making to improve pain management and, hence, the quality of life of people with autoimmune diseases in Africa.
- Subjects
AFRICA; AUTOIMMUNE diseases; CHRONIC pain; PAIN management; RESEARCH protocols; CINAHL database
- Publication
PLoS ONE, 2024, Vol 19, Issue 7, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0306564