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- Title
The frequency and severity of symptoms of major depression in Chinese patients with chronic, medically unexplained, painful physical symptoms who present to a general neurology clinic.
- Authors
Jianping Jia; Wei Qu; Weiping Wu; Liyong Wu; Lingqiu Meng; Dong Zhou; Zhen Hong; Joel Raskin; Holt, Susanna; Walton, Richard; Shenghu Wu
- Abstract
This cross-sectional, non-interventional, observational study evaluated depression in patients in China who presented to a general neurologist with chronic, medically unexplained, painful physical symptoms. Of the 402 patients enrolled, 197 patients (49.0%) met the criteria for a current major depressive episode (MDE+ group), as assessed using module A of the Mini International Neuropsychiatric Interview, and 205 patients (51.0%) did not (MDE- group). The mean pain severity visual analogue scale (VAS) score was significantly higher in the MDE+ group than the MDE- group (65.3 vs 55.6 mm; p<0.001). The mean depression severity score, as assessed using the 9-item Patient Health Questionnaire (PHQ-9), was 8.4 units (95% CI: 7.3 to 9.5) higher in the MDE+ group than the MDE- group (mean PHQ-9 total score: 14.8 vs 6.4). Anxiety and perceived health state were significantly worse, on average, in the MDE+ group (mean Hospital Anxiety and Depression Scale anxiety subscale score 10.7 vs 5.9 units; mean EuroQoL-5 Dimensions VAS score 56.4 vs 67.7 mm; each p<0.001). Only 14.2% of patients had received treatment for depression during the past 3 months. These results suggest depression was common and may have been under-treated in this group of Chinese patients with chronic, medically unexplained painful physical symptoms.
- Subjects
CHINA; MENTAL depression; ANXIETY; DEPRESSED persons; PSYCHOLOGICAL stress
- Publication
Neurology Asia, 2011, Vol 16, Issue 4, p329
- ISSN
1823-6138
- Publication type
Article