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- Title
Seizures Associated with Ofloxacin Therapy.
- Authors
Traeger, Sheldon M.; Bonfiglio, Mark F.; Wilson, James A.; Martin, Bradley R.; Nackes, Nicholas A.
- Abstract
We describe four patients who had seizures while receiving ofloxacin;no other causes were evident. Common factors among all patients included advanced age and use of a high-dose regimen. The renal insufficiency of three patients and the timing of the seizures implicate accumulation of ofloxacin as a contributing factor. Other potentially related factors included electrolyte abnormalities and prior neurological insult. Improved awareness of and further investigation into the neurotoxic effects of ofloxacin may enhance its safe use.
- Publication
Clinical Infectious Diseases, 1995, Vol 21, Issue 6, p1504
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/clinids/21.6.1504