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- Title
Efficacy of Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema After Vitrectomy.
- Authors
Watanabe, Akira; Tsuzuki, Akane; Arai, Kota; Gekka, Tamaki; Kohzaki, Kenichi; Tsuneoka, Hiroshi
- Abstract
<bold>Purpose: </bold>To compare the efficacy of intravitreal injection of triamcinolone acetonide (IVTA) for diabetic macular edema (DME) in vitrectomized eyes with DME without vitrectomy eyes.<bold>Methods: </bold>This retrospective comparative study evaluated the efficacy of IVTA treatment of DME in 26 consecutive eyes (23 patients). Changes in mean best-corrected visual acuity (VA) and mean central retinal thickness (CRT) were retrospectively evaluated before IVTA and during the 6-month period after IVTA.<bold>Results: </bold>Subjects were divided into 2 groups: 13 consecutive eyes (11 patients) with proliferative diabetic retinopathy or DME that underwent vitrectomy (vitrectomized group), and 13 consecutive eyes (12 patients) with DME who received IVTA, but did not undergo vitrectomy (nonvitrectomized group). In the vitrectomized group, there was a significantly decreased CRT for up to 4 months as compared to the thicknesses before IVTA. In the nonvitrectomized group, there was a significantly decreased CRT for up to 5 months after IVTA. In both groups, there was significant improvement in the VA for up to 4 months after IVTA.<bold>Conclusion: </bold>IVTA may represent a valid treatment option for DME, even in vitrectomized eyes.
- Subjects
TRIAMCINOLONE acetonide; DIABETIC retinopathy treatment; VITRECTOMY; DRUG efficacy; COMPARATIVE studies; RETROSPECTIVE studies; THERAPEUTICS; DIABETIC retinopathy; OPHTHALMIC surgery; RESEARCH methodology; MEDICAL cooperation; RESEARCH; RETINAL degeneration; EVALUATION research; TRIAMCINOLONE; OPTICAL coherence tomography
- Publication
Journal of Ocular Pharmacology & Therapeutics, 2016, Vol 32, Issue 1, p38
- ISSN
1080-7683
- Publication type
journal article
- DOI
10.1089/jop.2015.0045