We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
observed relationship between the degree of parasite aggregation and the prevalence of infection within human host populations for soil-transmitted helminth and schistosome infections.
- Authors
Kura, Klodeta; Truscott, James E; Collyer, Benjamin S; Phillips, Anna; Garba, Amadou; Anderson, Roy M
- Abstract
Background Soil-transmitted helminths (STH) and schistosome parasites are highly aggregated within the human population. The probability distribution of worms per person is described well by the negative binomial probability distribution with aggregation parameter, k , which varies inversely with parasite clustering. The relationship between k and prevalence in defined populations subject to mass drug administration is not well understood. Methods and Results We use statistical methods to estimate k using two large independent datasets for STH and schistosome infections from India and Niger, respectively, both of which demonstrate increased aggregation of parasites in a few hosts, as the prevalence of infections declines across the dataset. Conclusions A greater attention needs to be given in monitoring and evaluation programmes to find and treat the remaining aggregates of parasites.
- Subjects
NIGER; INDIA; HELMINTHIASIS; NEGATIVE binomial distribution; DISTRIBUTION (Probability theory); PARASITES
- Publication
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2022, Vol 116, Issue 12, p1226
- ISSN
0035-9203
- Publication type
Article
- DOI
10.1093/trstmh/trac033