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- Title
Dedifferentiated liposarcoma of the liver.
- Authors
Kim, Yong Il; Yu, Eun Sil; Lee, Keun Wook; Park, Eui U; Song, Hyung Geun; Kim, Y I; Yu, E S; Lee, K W; Park, E U; Song, H G
- Abstract
Among the rare occurrences of primary malignant mesenchymal tumors of the liver, the development of liposarcoma has been only theoretically listed--there is no proven example in the literature. This article documents a case of primary liposarcoma of the liver in a 30-year-old woman who presented with a huge intrahepatic tumor in the left lobe measuring 14 X 10 X 6 cm. It was composed of two distinct macroscopic and histologic features--the well-differentiated liposarcoma and the cellular, nonlipogenic pleomorphic sarcoma. The former was a mature, lipomatous tumor with various stages of lipoblasts. The latter was much more cellular, made up of pleomorphic cells admixed with a few areas of spindle cells with many mitotic figures, resembling a pleomorphic variant of malignant fibrous histiocytoma. Oil red O stain revealed multifocal, but a scanty amount, of fat-storing tumor cells in both compartments aside from large fat globules in the differentiated area. This is the first reported case of primary liposarcoma of the liver.
- Publication
Cancer (0008543X), 1987, Vol 60, Issue 11, p2785
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19871201)60:11<2785::AID-CNCR2820601131>3.0.CO;2-O