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- Title
Feasibility analysis of low-dose CT with asynchronous quantitative computed tomography to assess vBMD.
- Authors
Hu, Tingting; Yang, Xingyuan; Gao, Lei; Liu, Ying; Zhang, Wei; Wang, Yan; Zhu, Xiaona; Liu, Xiangdong; Liu, Hongran; Ma, Xiaohui
- Abstract
Background: To explore the feasibility of low-dose computed tomography (LDCT) with asynchronous quantitative computed tomography (asynchronous QCT) for assessing the volumetric bone mineral density (vBMD). Methods: 416 women patients, categorized into 4 groups, were included and underwent chest CT examinations combined with asynchronous QCT, and CT scanning dose protocols (LDCT or CDCT) were self-determined by the participants. Radiation dose estimations were retrieved from patient protocols, including volume CT dose index (CTDIvol) and dose-length-product (DLP), and then calculated effective dose (ED). Delimiting ED by 1.0 mSv, chest CT examinations were categorized into 2 groups, LDCT group and CDCT group. vBMD of T12-L2 was obtained by transferring the LDCT and CDCT images to the QCT workstation, without extra radiation. Results: There was no difference of vBMD among 4 age groups in LDCT group (P = 0.965), and no difference in CDCT group (P = 0.988). In LDCT group and CDCT group, vBMD was not correlated to mAs, CTDIvol and DLP (P > 0.05), respectively. Between LDCT group and CDCT group, there was no difference of vBMD (P ≥ 0.480), while differences of mAs, CTDIvol and DLP. Conclusion: There was no difference of vBMD between LDCT group and CDCT group and vBMD was not correlated to mAs. While screening for diseases such as lung cancer and mediastinal lesions, LDCT combined with asynchronous QCT can be also used to assess vBMD simultaneously with no extra imaging equipment, patient visit time, radiation dose and no additional economic cost.
- Subjects
COMPUTED tomography; CONE beam computed tomography; BONE density; MEDICAL screening; CHEST examination
- Publication
BMC Medical Imaging, 2023, Vol 23, Issue 1, p1
- ISSN
1471-2342
- Publication type
Article
- DOI
10.1186/s12880-023-01115-1