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- Title
Variant Plasmodium ovale isolated from a patient infected in Ghana.
- Authors
Tordrup, David; Virenfeldt, Jakob; Andersen, Felicie F.; Petersen, Eskild
- Abstract
Recent data have found that Plasmodium ovale can be separated in two distinct species: classic and variant P. ovale based on multilocus typing of different genes. This study presents a P. ovale isolate from a patient infected in Ghana together with an analysis of the small subunit RNA, cytochrome b, cytochrome c oxidase I, cysteine protease and lactate dehydrogenase genes, which show that the sample is a variant P. ovale and identical or highly similar to variant P. ovale isolated from humans in South-East Asia and Africa, and from a chimpanzee in Cameroon. The split between the variant and classic P. ovale is estimated to have occurred 1.7 million years ago.
- Subjects
AFRICA; GHANA; PLASMODIUM; LACTATE dehydrogenase; CYTOCHROMES
- Publication
Malaria Journal, 2011, Vol 10, Issue 1, p15
- ISSN
1475-2875
- Publication type
Article
- DOI
10.1186/1475-2875-10-15