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- Title
Environmental Tobacco Smoke and the Risk of Pancreatic Cancer.
- Authors
Villeneuve, Paul J.; Johnson, Kenneth C.; Yang Mao; Hanley, Anthony J.
- Abstract
Despite the fact that tobacco is a well-recognized risk factor for pancreatic cancer, no study has yet reported on the association between environmental tobacco smoke (ETS) and this malignancy. We investigated the relationship between pancreatic cancer and childhood and adult exposure to ETS using a case-control study design. Among never smokers, those who were exposed to ETS both as a child and as an adult had an odds ratio of 1.21 (95% C1=0.60–2.44) relative to those with no exposure. For active smoking, when the referent group consisted of never smokers who had not been regularly exposed to ETS, the risk increases were more pronounced with an increased number of years of smoking, cigarette pack-years, years since quit smoking, and average number of cigarettes smoked daily. Overall, our results are suggestive of a weak association between pancreatic cancer and ETS. Perhaps more importantly, they suggest that ETS smoking exposures may confound the risk of pancreatic cancer associated with active smoking measures commonly used in epidemiologic studies.
- Subjects
TOBACCO smoke pollution; INDOOR air pollution; PANCREATIC cancer; ENDOCRINE gland cancer; CANCER risk factors; ETIOLOGY of diseases
- Publication
Canadian Journal of Public Health, 2004, Vol 95, Issue 1, p32
- ISSN
0008-4263
- Publication type
Article
- DOI
10.1007/bf03403631