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- Title
Lesions Accompanying Fibrocystic Changes in The Breast: A Retrospective Study.
- Authors
Koyuncu, Nida Meriç; Ersoy, Yeliz Emine; Yıldız, Şeyma; Gucin, Zuhal
- Abstract
Objective: Fibrocystic breast disease (FBD) is the most common benign condition of the breast. Although it is not usually associated with breast cancer, some studies suggest that fibrocystic changes (FCs) increase the risk. The diagnosis is made by clinical examination in 50% and by histopathological studies in 90% of women. The pathogenesis of FCs is still unclear, but exaggerated response to hormones is thought to be responsible. The aim of our study was the investigation of lesions accompanying FCs and conditions that might be important on the course. Method: Radiology and pathology results of the patients who applied to general surgery breast polyclinic in 2019 were scanned retrospectively from Bezmialem Vakıf University Hospital data (Bizmed). Patients who were radiologically diagnosed with heterogeneously and extremely dense breasts, which might obscure small masses or lower the sensitivity of mammography, based on ACR BI-RADS Atlas were included. We investigated the additional lesions, lesion characteristics, histopathological evaluations and connection with etiologic factors. Results: In this study, 393 female patients were included (227 premenopausal, 166 postmenopausal). Forty five were ≤40 years old and 348 were >40 years old. Among the premenopausal patients; 46 had dense fibrocystic changes, 103 had benign mass, 54 had suspicious micro calcifications and 24 had malignant mass in mammography. Biopsy results were found to be significantly malignant (23 pts, 95.8%) in the patient group whose mammography also showed lesions suspicious for malignancy (p<0.001). Among the postmenopausal patients; 26 had dense fibrocystic changes, 69 had benign mass, 49 had suspicious micro calcifications and 22 had malignant mass in mammography. In the patient group with malignant mass on mammography, biopsy results were found to be significantly malignant (21 pts, 95.5%) (p<0.001) Conclusion: In women with FBD, the evaluation of mammography requires experience because the dense structure of the breasts decreasing the sensitivity and additional lesions should be evaluated carefully.
- Subjects
BREAST; MAMMOGRAMS; BREAST surgery; WOMEN patients; RETROSPECTIVE studies; FIBROADENOMAS; ADNEXAL diseases
- Publication
Bezmialem Science, 2020, Vol 8, pS69
- ISSN
2148-2373
- Publication type
Article