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- Title
Total Parenteral Nutrition Is a Major Risk Factor for Central Venous Catheter-Related Bloodstream Infection in Colorectal Cancer Patients Receiving Postoperative Chemotherapy.
- Authors
Ishizuka, M.; Nagata, H.; Takagi, K.; Kubota, K.
- Abstract
Purpose: To clarify the risk factors for central venous catheter-related bloodstream infection (CVCR-BSI) in patients receiving chemotherapy after surgery for colorectal cancer (CRC). Methods: CVCR-BSI was evaluated retrospectively from a database of patients who had received postoperative chemotherapy using central venous catheters (CVC). Results: One hundred and nine patients received 542 CVC for a total of 5,558 catheter-days. There were no significant differences in background between the patients who had CVCR-BSI and those who did not, except for the administration of total parenteral nutrition (TPN) (p < 0.0001). Moreover, univariate analyses (using factors including type of catheter, sex, age, troubles with insertion, kinds of disinfectant, kinds of catheter, length of inserted catheter, term of catheter insertion and administration of TPN) revealed that the administration of TPN (odds ratio, 12.74; 95% CI, 2.489–62.26; p = 0.0023) was the only risk factor for CVCR-BSI. Conclusions: TPN is a major risk factor for CVCR-BSI in CRC patients receiving postoperative chemotherapy. Copyright © 2008 S. Karger AG, Basel
- Subjects
COLON cancer; COLON surgery; TOTAL parenteral feeding; CATHETERIZATION complications; PREOPERATIVE risk factors; DRUG therapy
- Publication
European Surgical Research, 2008, Vol 41, Issue 4, p341
- ISSN
0014-312X
- Publication type
Article
- DOI
10.1159/000160181