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- Title
Effects of mycophenolate mofetil on acute ischaemia–reperfusion injury in rats and its consequences in the long term.
- Authors
Sabbatini, Massimo; Uccello, Francesco; Serio, Vittorio; Troncone, Giancarlo; Varone, Valeria; Andreucci, Michele; Faga, Teresa; Pisani, Antonio
- Abstract
Background. Renal ischaemia–reperfusion injury (IRI) acutely decreases glomerular filtration rate (GFR) and impairs kidney function in the long term. Pre-treatment with chaetomellic acid (KM), an inhibitor of membrane-bound Ha-Ras, has demonstrated beneficial effects on acute renal ischaemia.
- Subjects
ISCHEMIA; KIDNEY diseases; REPERFUSION injury; BLOOD circulation disorders; CARDIOVASCULAR diseases
- Publication
Nephrology Dialysis Transplantation, 2010, Vol 25, Issue 5, p1443
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/gfp710