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- Title
Accidental alfaxalone overdose in a mature cat undergoing anaesthesia for magnetic resonance imaging.
- Authors
Bayldon, Wendy; Carter, Jennifer E.; Beths, Thierry; Warne, Leon N.; Whittem, Ted; Martinez, Lorena; Bauquier, Sébastien H.
- Abstract
Case summary This case report describes the clinical signs and treatment of an alfaxalone 10 times overdose in a 12-year-old cat undergoing anaesthesia for MRI. The cat was discharged from hospital following a prolonged recovery including obtunded mentation and cardiorespiratory depression for several hours following cessation of anaesthesia. The cat received supportive therapy that included supplemental oxygen via a face mask, intravenous crystalloid fluids and active rewarming. The benefits of using alfaxalone for maintenance of anaesthesia, its pharmacokinetics and previously reported lethal doses are discussed. Strategies for reducing the incidence of medication errors are presented. Relevance and novel information An unintentional overdose of alfaxalone by continuous rate infusion has not been reported previously in a cat. Treatment is supportive and directed towards maintenance of the cardiorespiratory systems. Whenever possible, smart pumps that have been designed to reduce human error should be used to help prevent medication errors associated with continuous rate infusions.
- Publication
Journal of Feline Medicine & Surgery Open Reports, 2016, Vol 2, Issue 1, p1
- ISSN
2055-1169
- Publication type
Article
- DOI
10.1177/2055116916647740