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- Title
A comparative study on the choroidal vascularity index and the determination of cut-off values in the pachychoroid spectrum diseases.
- Authors
Demirel, Sibel; Yanık, Özge; Özcan, Gökçen; Batıoğlu, Figen; Özmert, Emin
- Abstract
Purpose: To determine the cut-off levels for choroidal thickness and choroidal vascularity index (CVI) to differentiate among pachychoroid spectrum diseases. Study design: A retrospective comparative study Methods: A total of 143 eyes were included. Of these 29 had uncomplicated pachychoroid (UCP), 29 had pachychoroid pigment epitheliopathy (PPE), 25 had pachychoroid neovasculopathy (PNV), 30 had central serous chorioretinopathy (CSC), and 30 had polypoidal choroidal vasculopathy (PCV). The choroidal areas were measured with ImageJ software. The CVI, the proportion of the luminal area to the total choroidal area, was assessed. Results: The cut-off points of central choroidal thickness were determined as 360 µm for the PPE and PCV group pair (p < 0.001), 422 µm for the PNV and CSC group pair (p = 0.026), 271 µm for the PNV and PCV group pair (p < 0.001), and 341 µm for the CSC and PCV group pair (p < 0.001). The cut-off points of CVI were 72.7 for the PPE and PCV group pair (p < 0.001), 74.7 for the PNV and CSC group pair (p = 0.005), 72.6 for the PNV and PCV group pair (p = 0.001), and 73.6 for the CSC and PCV group pair (p < 0.001). Conclusion: Pachychoroid spectrum may be composed of a combination of distinct choroidal diseases with different vascular and structural characteristics.
- Subjects
CHOROID; POLYPOIDAL choroidal vasculopathy; CHOROID diseases; COMPARATIVE studies
- Publication
Japanese Journal of Ophthalmology, 2021, Vol 65, Issue 4, p482
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-021-00829-5