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- Title
Insulin secretion and its association with physical activity, fitness and screen time in children.
- Authors
Henderson, M.; Gray‐Donald, K.; Rabasa‐Lhoret, R.; Bastard, J.‐P.; Barnett, T. A.; Benedetti, A.; Chaput, J.‐P.; Tremblay, A.; Lambert, M.
- Abstract
Objectives To determine the independent associations of moderate to vigorous physical activity (MVPA), fitness, screen time, and adiposity with insulin secretion in children. Design and Methods Caucasian youth ( n = 423/630), 8-10 years old, with at least one obese biological parent, were studied (QUALITY cohort). Insulin secretion was measured using HOMA2-%B, area under the curve (AUC) of insulin to glucose over the first 30 minutes (AUC I/Gt30min) of the OGTT and AUC I/Gt120min over 2 hours. Fitness was measured by VO2peak; percent fat mass (PFM) by DXA; 7-day MVPA by accelerometry; self-reported screen time included television, video game, or computer use. Models were adjusted for age, sex, season, puberty, PFM, and insulin sensitivity [IS] (HOMA2-IS, Matsuda-ISI). Results PFM was strongly associated with insulin secretion, even after adjustment for IS: for every 1% increase in PFM, insulin secretion increased from 0.3% to 0.8% across indices. MVPA was negatively associated with HOMA2-%B ( P < 0.05), but not with OGTT-derived measures. Fitness was negatively associated with AUC I/Gt120min ( P < 0.05). Screen time showed a trend toward higher HOMA2-%B in girls ( P = 0.060). Conclusions In children with an obese parent, lower insulin secretion is associated with lower adiposity, higher MVPA, better fitness, and possibly reduced screen time.
- Subjects
CHILDREN'S health; HORMONE receptors; PHYSICAL activity; INSULIN research; BODY weight
- Publication
Obesity (19307381), 2014, Vol 22, Issue 2, p504
- ISSN
1930-7381
- Publication type
Article
- DOI
10.1002/oby.20619