We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Fresh fruit, dried fruit, raw vegetables, and cooked vegetables consumption associated with progression trajectory of type 2 diabetes: a multi-state analysis of a prospective cohort.
- Authors
Zheng, Guzhengyue; Ran, Shanshan; Zhang, Jingyi; Qian, Aaron M.; Hua, Junjie; Wang, Chongjian; Vaughn, Michael G.; Tabet, Maya; Lin, Hualiang
- Abstract
Purpose: To examine the effects of fresh fruit, dried fruit, raw vegetables, and cooked vegetables on type 2 diabetes (T2D) progression trajectory. Methods: We included 429,886 participants in the UK Biobank who were free of diabetes and diabetes complications at baseline. Food groups were determined using a validated food frequency questionnaire. Outcomes were T2D incidence, complications, and mortality. Multi-state model was used to analyze the effects of food groups on T2D progression. Results: During a follow-up of 12.6 years, 10,333 incident T2D cases were identified, of whom, 3961 (38.3%) developed T2D complications and 1169 (29.5%) died. We found that impacts of four food groups on T2D progression varied depending on disease stage. For example, compared to participants who ate less than one piece of dried fruit per day, the hazard ratios and 95% confidence intervals for those who ate ≥ 2 pieces of dried fruit per day were 0.82 (0.77, 0.87), 0.88 (0.85, 0.92), and 0.86 (0.78, 0.95) for transitions from diabetes-free state to incident T2D, from diabetes-free state to total death, and from incident T2D to T2D complications, respectively. Higher intake of fresh fruit was significantly associated with lower risk of disease progression from diabetes-free state to all-cause death. Higher intake of raw and cooked vegetables was significantly associated with lower risks of disease progression from diabetes-free state to incident T2D and to total death. Conclusions: These findings indicate that higher intake of fresh fruit, dried fruit, raw vegetables, and cooked vegetables could be beneficial for primary and secondary prevention of T2D.
- Subjects
UNITED Kingdom; FRUIT; FOOD consumption; RESEARCH funding; QUESTIONNAIRES; VEGETABLES; TYPE 2 diabetes; CONFIDENCE intervals; DISEASE relapse; DISEASE progression; MEDICAL incident reports
- Publication
European Journal of Nutrition, 2024, Vol 63, Issue 5, p1719
- ISSN
1436-6207
- Publication type
Article
- DOI
10.1007/s00394-024-03362-6