We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
NbCl<sub>5</sub>+AgClO<sub>4</sub> AS A VERSATILE COMBINED CATALYST SYSTEM FOR AN ACCELERATED SYNTHESIS OF 1, 4- DIHYDROPYRIDINE SCAFFOLDS.
- Authors
Bora, Manisha; Kadam, Kailas; Wani, Punam; Kamble, Narendra
- Abstract
Herein presented work describes the catalytic potential of NbCl5+AgClO4 as a combined and convenient catalyst system for a straightforward, safe, quick, and single-pot synthesis of 1, 4-dihydropyridine (DHP) scaffolds. It was investigated that a small amount of NbCl5+AgClO4 is sufficient and potential enough to bring out the solvent-free synthesis of 1, 4-dihydropyridine scaffolds from a three-components, the cyclic reaction between substituted aldehyde(s), ethyl-3-oxobutanoate, and ammonium ethanoate. It is noteworthy to mention that good to excellent yields of DHPs were achieved by developing an environmentally compatible, sustainable, mild, and simple synthetic protocol. A range of differently substituted aldehydes was observed to undergo herein developed catalytic protocol smoothly to offer good yields of DHPs in 3 to 5 h at room temperature. Representative DHPs are characterized by adequate analytical techniques such as FTIR, ¹HNMR, 13CNMR, and mass spectrometric techniques.
- Subjects
DIHYDROPYRIDINE; CATALYSTS; ALDEHYDES; AMMONIUM acetate; AMMONIUM
- Publication
Rasayan Journal of Chemistry, 2022, Vol 15, Issue 4, p2596
- ISSN
0974-1496
- Publication type
Article
- DOI
10.31788/RJC.2022.1548086