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- Title
Schoolchildren born VLBW or VLGA show height-related changes in body composition and muscle function but no evidence of metabolic syndrome risk factors. Results from the NEOLONG study.
- Authors
Ranke, Michael B.; Schweizer, Roland; Rodemann, Susanne M.; Bevot, Andrea; Martin, David D.; Goelz, Rangmar; Wollmann, Hartmut A.; Krägeloh-Mann, Ingeborg; Binder, Gerhard
- Abstract
Background: Children born small for gestational age (SGA) are at risk for the metabolic syndrome (MetS) as adults. We examined whether indicators of MetS could be identified in pre-pubertal children born very preterm. Methods: Parameters associated with MetS were studied in 141 pre-pubertal schoolchildren with either very low birth weight (VLBW) or GA <32 weeks (SGA: n=43). Results: At 8.3±0.8 years, 36 children (SGA: n=15) were classified short. There were no differences between the SGA and appropriate for age (AGA) groups; nor were dissimilarities observed between short children and those with normal height for parameters such as body mass index (BMI), serum levels of hormones, HDL cholesterol, triglycerides, glucose, insulin, HOMA-IR, body composition, resting energy expenditure, grip strength and jump force. Conclusions: Neither SGA at birth nor short stature at follow-up (irrespective of size at birth), could be associated with parameters that indicate an increased risk for the MetS during childhood.
- Publication
Journal of Pediatric Endocrinology & Metabolism, 2016, Vol 29, Issue 2, p163
- ISSN
0334-018X
- Publication type
Article
- DOI
10.1515/jpem-2015-0266