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- Title
绝经早期妇女小剂量利维爱治疗对靶器官的影响.
- Authors
盛 秋; 赵巧玲; 刘会婷; 李 芬
- Abstract
Objective To explore the effects of small-dose Livial treatment on the target organ of early menopausal women. Methods Random opening method was used. Totally 132 postmenopausal women were selected as the study group and were given Livial 1.25mg/d once a day. The uterus volume, endometrial thickness, ovarian area and breast structure of the subjects were observed with ultrasonic measurement both before and 1 year after administration of Livial. They were compared with those in the control group. Results The difference in uterus volume before and after administration of Livial was not significant (P>0.05); the degree of atrophy was mild compared with that in the control group (P<0.05). There were no significant differences in endometrial thickness and ovarian area between the study group and the control group and between study group before and after administration of Livial (P>0.05). The glandular layer was thicker and mammary duct diameter was shorter in the study group, but the two groups did not significantly differ (P>0.05). Conclusion Postmenopausal administration of small-dose Livial may decrease the degree of uterus atrophy, but does not have obvious effects on endometrial thickness, ovarian area, thickness of glandular layer or mammary duct diameter. The long-term effect needs to be followed up for a long time.
- Subjects
HORMONE therapy for menopause; MENSTRUAL cycle; CONTROL groups; OVARIAN cysts; BREAST diseases; ATROPHY
- Publication
Journal of Xi'an Jiaotong University (Medical Sciences), 2014, Vol 35, Issue 2, p267
- ISSN
1671-8259
- Publication type
Article
- DOI
10.7652/jdyxb201402027