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- Title
STATIC MAGNETIC FIELD OF COMMERCIAL SAMARIUM-COBALT (SMCO5) ORTHODONTIC MAGNETS AND DNA FRAGMENTATION OF HUMAN LYMPHOCYTE CELLS.
- Authors
Abdel-Kader, Hussam M.; Aref, Mohamed I.; Yousef, Sedky W.
- Abstract
Objective: The current study aimed to investigate the biological effects of the static magnetic fields of commercially available orthodontic samarium-cobalt (SmCo5) magnets on cultured human lymphocyte cells. Materials and methods: To study the effect of the static magnetic field, in attraction and repelling modes, on human lymphocyte cells, two couples of orthodontic magnets were used. One couple was fixed with the magnets in attraction mode and the second one; the two magnets were fixed in repelling mode. On the other hand, three autoclaved glass laboratory tubes were prepared and filled with cultured human lymphocyte cells. One tube was used as a control sample and the other two were used as test samples. Each couple of the prepared orthodontic magnets was threaded into silk thread, immersed and positioned exactly in the center of the cultured lymphocytes. Modified comet assay was used to evaluate the biological effects of exposing the human lymphocyte cells for 48 hours to the static magnetic field of orthodontic magnets under repelling and attraction modes. Results: 1. The percentage of DNA fragmented human lymphocyte cells recorded statistically significant level (P ≤ 0.001) after exposure for 48 hours to the static magnetic field of orthodontic magnets. 2. The adverse biological effects of the static magnetic field in attraction mode were significantly higher than that recorded in magnets' repelling mode. Conclusion: 1. Short time exposure (48 hours) of human lymphocyte cells to the static magnetic field of the commercially used orthodontic samarium-cobalt (SmCo5) magnets will end with significant DNA fragmentation of those cells. 2. The static magnetic field of magnets fixed in attraction mode has significantly higher adverse biological effects compared to that fixed in repelling mode. 3. Iron is important dynamic to augment that effect.
- Subjects
SAMARIUM compounds; RARE earth metals; ORTHODONTICS; DNA; LYMPHOCYTES; MONONUCLEAR leukocytes
- Publication
International Journal of Clinical Dentistry, 2012, Vol 5, Issue 4, p363
- ISSN
1939-5833
- Publication type
Article