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- Title
<sup>18</sup>F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor.
- Authors
KEBIR, SIED; KIMMICH, OKKA; NIEHUSMANN, PITT; GAERTNER, FLORIAN C.; ESSLER, MARKUS; LANDSBERG, JENNIFER; KLOCKGETHER, THOMAS; SIMON, MATTHIAS; HERRLINGER, ULRICH; GLAS, MARTIN
- Abstract
Diagnosis in patients with a suspected malignant intramedullary lesion that requires biopsy for definitive diagnosis may be challenging, as spinal cord surgery carries the risk of irreversible neurological deficits. The current study presents the first case of 18F-fluoroethyl-L-tyrosine (18F-FET) positron emission tomography (PET) imaging in a patient with a spinal cord tumor. The patient was unsuitable for magnetic resonance imaging due to his implanted cardiac defibrillator. 18F-FET PET indicated a high-grade malignancy of the spinal cord, justifying tumor biopsy. Histological analysis was compatible with a malignant melanoma. This is also the first report demonstrating the FET-PET appearance/metabolic phenotype of a malignant melanoma of the spinal cord.
- Subjects
TYROSINE; SPINAL cord tumors; POSITRON emission tomography; SPINAL cord surgery; DEFIBRILLATORS; DIAGNOSIS
- Publication
Oncology Letters, 2016, Vol 12, Issue 6, p4705
- ISSN
1792-1074
- Publication type
Article
- DOI
10.3892/ol.2016.5234