We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Detection and Treatment of Helicobacter pylori: Problems and Advances.
- Authors
Yang, Hang; Guan, Liwen; Hu, Bing
- Abstract
Helicobacter pylori (H. pylori) infection is chronic and etiologically linked to gastric cancer (GC) derived from gastric epithelium. The potential mechanism is complex, covering chronic inflammation, epithelial senescence, NF-κB activation, the cytotoxin-associated gene A protein translocation, and related abnormal signaling pathways. In clinical practice, the test-and-treat strategy, endoscopy-based strategy, and (family-based) screen-and-treat strategy are recommended to detect H. pylori and prevent GC. It has been demonstrated that the decreasing annual incidence of GC is largely attributable to the management of H. pylori. This study reviews the current clinical practice of H. pylori on the detection and eradication, alternative treatment strategies, and related problems and advances, and hopes to contribute to the better clinical management of H. pylori.
- Subjects
HELICOBACTER disease diagnosis; STOMACH tumors; HELICOBACTER pylori; CELLULAR signal transduction; HELICOBACTER diseases; EARLY diagnosis; DISEASE management
- Publication
Gastroenterology Research & Practice, 2022, Vol 2022, p1
- ISSN
1687-6121
- Publication type
Article
- DOI
10.1155/2022/4710964