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- Title
Smell Outcome and Seropositivity Titre in Post-COVID-19 Patients.
- Authors
Harminder Singh, Shalina Kaur; Husain, Salina; Wan Hamizan, Aneeza Khairiyah; Zahedi, Farah Dayana; Othman, Siti Norlia; Zainol Rashid, Zetti
- Abstract
Introduction: The aims of the study were to perform an olfactory assessment on patients active and post-COVID-19 using the culturally adapted Malaysian version Sniffin' Sticks identification smell test (mSS-SIT), to evaluate the patient olfactory outcome using a Malay short version of the Questionnaire of Olfactory Disorders-Negative Statements (msQOD-NS), as well as to evaluate seropositive titre (IgG) response using automated serology method. Methods: Score for mSS-SIT was performed during the hospitalization, when patients had tested positive for SARS-CoV-2 (during COVID-19), and repeated after they had tested negative (after COVID-19). Also, each patient completed msQOD-NS and serology SARS-CoV-2 antibodies blood test was evaluated. Results: During COVID-19, 2 of our patients were anosmia (6.5%), 22 (70.9%) were hyposmia, and 7 (22.6%) were normosmia. We repeated mSS-SIT on these same patients after COVID-19, and none of these subjects were hyposmia or anosmia, as they achieved a score >12. All our patients had scored 21 using msQOD-NS, meaning no impact on quality of life as they had regained their normal olfactory function. In this study also, we obtained no correlation between smell test and seropositivity titre COVID-19, and antibody levels gradually decreased over time till 6 months and remained stable up to 12 months. Conclusion: From this study, we know full recovery of the sense of smell can be expected post-COVID-19 infection and COVID-19 antibody persists in the body up to 12 months of infection.
- Subjects
COVID-19 pandemic; COVID-19; SEROCONVERSION; OLFACTOMETRY; TITERS
- Publication
ORL, 2023, Vol 85, Issue 6, p305
- ISSN
0301-1569
- Publication type
Article
- DOI
10.1159/000531222