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- Title
Analysis of the Angiotensinogen Gene T174M Polymorphism in Populations of the Volga–Ural Region.
- Authors
Nasibullin, T. R.; Mustafina, O. E.; Tuktarova, I. A.; Danilova, V. V.; Khusnutdinova, E. K.
- Abstract
The method of polymerase chain reaction was used to analyze T174M polymorphism at the angiotensinogen (AGT) gene in a number of populations of the Volga–Ural region, belonging to Finno–Ugric (Komi-Permyaks, Maris, Mordovians, and Udmurts), Turkic (Chuvashes, Tatars, and Bashkirs), and Eastern-Slavic (Russians) ethnic groups. Population-specific patterns of the polymorphic alleles and genotypes frequency distribution were established. Comparison of the results with the literature data on the AGT gene polymorphism in different world populations provided identification of specific trends in the changes of genotype frequency of the AGT gene depending on the ethnicity of the populations.
- Subjects
HUMAN population genetics; POPULATION genetics; GENETICS; HEREDITY; GENE frequency; ANGIOTENSINS
- Publication
Russian Journal of Genetics, 2004, Vol 40, Issue 10, p1163
- ISSN
1022-7954
- Publication type
Article
- DOI
10.1023/B:RUGE.0000044762.30487.19