We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Remission of necrobiotic xanthogranuloma after intravenous immunoglobulin interruption: A case report.
- Authors
Gilbert-Falardeau, Amélie; Drolet, Anne-Marie
- Abstract
Necrobiotic xanthogranuloma is a rare non-Langerhans cell histiocytosis with the potential for multisystemic involvement. It's a challenging disease to treat and multiple treatments have been reported in the literature with variable results. We present the case of a 92-year-old woman with multiple orange-brown papules and plaques on her face progressing for several years. The biopsy showed dermal xanthogranulomatous infiltration with multinucleated giant cells and necrobiosis, and she was diagnosed with necrobiotic xanthogranuloma. A complete response was obtained with intravenous immunoglobulins and she remained in remission despite treatment discontinuation.
- Subjects
NON-langerhans-cell histiocytosis; MULTINUCLEATED giant cells; TERMINATION of treatment; INTRAVENOUS immunoglobulins; ERDHEIM-Chester disease; BIOPSY
- Publication
SAGE Open Medical Case Reports, 2024, p1
- ISSN
2050-313X
- Publication type
Case Study
- DOI
10.1177/2050313X241274888