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- Title
EVIDENCE-BASED USE OF SEA BUCKTHORN FRESH JUICE FOR PATIENTS WITH TRAUMATIC BRAIN INJURY. A PILOT STUDY.
- Authors
GODEANU, CONSTANTIN SORIN; COSTEA, TEODORA; GHICA, MANUELA; LUPULIASA, DUMITRU; GÎRD, CERASELA ELENA
- Abstract
Sea buckthorn (Hippophaë rhamnoides L.) berries are widely used for their nutrional value and therapeutic effects. The aim of our paper was the evolution of phenolic content (by means of spectrophotometric methods), antioxidant capacity (scavenger activity towards DPPH, ABTS·+ free radicals and ferric reducing power) and evidence regarding sea buckthorn fresh juice association in the management of hospitalized patients with traumatic brain injury. According to our results, sea buckthorn fresh juice is a source of phenolic compounds (0.28 g total phenolic content expressed as tannic acid equivalents/100 mL fresh juice and 0.09 g flavones expressed as hyperoside equivalents/100 mL fresh juice), with antioxidant activity. Our clinical results have shown beneficial effects (a decrease in lactate and sodium blood levels and an increase in Glasgow coma score) of sea buckthorn fresh juice (given together with specific medication) in the management of patients with traumatic brain injury.
- Subjects
SEA buckthorn; BRAIN injuries; TANNINS; OXIDANT status; PHENOLS
- Publication
Farmacia, 2020, Vol 68, Issue 3, p541
- ISSN
0014-8237
- Publication type
Article
- DOI
10.31925/farmacia.2020.3.21