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- Title
Sustained suppression of enterohepatic circulation of mycophenolic acid by antimicrobial‐associated diarrhea in a kidney transplant recipient with Crohn's disease: A case report.
- Authors
Tanaka, Ryota; Matsumoto, Asami; Tatsuta, Ryosuke; Ando, Tadasuke; Shin, Toshitaka; Mimata, Hiromitsu; Itoh, Hiroki
- Abstract
Mycophenolic acid (MPA) undergoes enterohepatic circulation. A kidney transplant patient on mycophenolate mofetil was treated with tazobactam/piperacillin for pyelonephritis, and developed antimicrobial‐associated diarrhea. Consequently, the MPA trough level decreased by approximately 90%. Furthermore, it took approximately a month for the MPA level to normalize even after diarrhea had resolved.
- Subjects
CROHN'S disease; ENTEROHEPATIC circulation; MYCOPHENOLIC acid; KIDNEY transplantation; DIARRHEA; PYELONEPHRITIS
- Publication
Clinical Case Reports, 2022, Vol 10, Issue 6, p1
- ISSN
2050-0904
- Publication type
Case Study
- DOI
10.1002/ccr3.5914