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- Title
Virulence factors of Treponema denticola.
- Authors
Ishihara, Kazuyuki
- Abstract
The article focuses on the virulence factors of Treponema denticola including major outer sheath protein (Msp) and dentilisin which were analyzed using molecular genetic techniques. It says that development of animal models improves the apprehension of pathogenicity of T. denticola which allows detailed analysis and interaction with other periodontopathic bacteria in developing periodontitis. It adds that virulence factors of T. denticola are associated with chronic periodontitis development.
- Subjects
TREPONEMA; MICROBIAL virulence; MOLECULAR genetics; PERIODONTITIS; ANIMAL models in research
- Publication
Periodontology 2000, 2010, Vol 54, Issue 1, p117
- ISSN
0906-6713
- Publication type
Article
- DOI
10.1111/j.1600-0757.2009.00345.x