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- Title
Spindle cell tumour with S100 and CD34 co‐expression showing PDZRN3–RAF1 rearrangement – a recently described entity.
- Authors
Mok, Yingting; Lee, Victor K M; Kimpo, Miriam S; Chen, Huiyi; Kuick, Chik H; Chang, Kenneth T‐E
- Abstract
The article presents a case study of a 4-year old boy with an asymptomatic mass at the back of right thigh. The morphology and immunophenotype of the tumor corresponded to the characterized group of soft tissue spindle cell lesions defined by a relatively uniform cytomorphology, perivascular hyalinization, and S100 and CD34 coexpression. The article adds benefits of parallel sequencing as the types and number of gene fusions these tumors can render single-gene assay insensitive.
- Subjects
SPINDLE apparatus; CANCER cells; GENE expression; NUCLEOTIDE sequencing; BIOLOGICAL tags
- Publication
Histopathology, 2019, Vol 74, Issue 7, p1109
- ISSN
0309-0167
- Publication type
Case Study
- DOI
10.1111/his.13841