We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Editorial: Roles of Tumor-Recruited Myeloid Cells in Immune Evasion in Cancer.
- Authors
Kusmartsev, Sergei; Serafini, Paolo; Bharadwaj, Srinivas Nagaraj; Kortylewski, Marcin
- Abstract
Keywords: tumor microenvironment; immune evasion; immune tolerance; MDSC (myeloid-derived suppressor cell); tumor-associated macrophage EN tumor microenvironment immune evasion immune tolerance MDSC (myeloid-derived suppressor cell) tumor-associated macrophage 1 4 4 09/01/21 20210827 NES 210827 During tumor formation and progression, tumors develop an immunosuppressive and tolerogenic microenvironment. Myeloid cell recruitment into tumors is associated with enhanced tumor-induced myelopoiesis and inflammation, which drives mobilization of myeloid cells to the tumor site. These methods may provide a greater understanding of the mechanisms of tumor-associated immune suppression and tolerance, differentiation and polarization of myeloid cells in the tumor microenvironment, and interaction of tumor-infiltrating myeloid cells with immune cells, tumor cells, and stromal compartment.
- Subjects
MYELOID cells; MELANOMA; MYELOID-derived suppressor cells; CANCER cells; MACROPHAGE migration inhibitory factor; TUMOR-infiltrating immune cells
- Publication
Frontiers in Immunology, 2021, Vol 12, p1
- ISSN
1664-3224
- Publication type
Editorial
- DOI
10.3389/fimmu.2021.749605