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- Title
Frequency and predictors of proxy-confirmed post-stroke cognitive complaints in lacunar stroke patients without major depression.
- Authors
Xiong, Yun-Yun; Wong, Adrian; Mok, Vincent C. T.; Tang, Wai-Kwong; Lam, Wynnie W. M.; Kwok, Timothy C. Y.; Chu, Winnie C. W.; Chan, Anne Y. Y.; Wong, Lawrence K. S.
- Abstract
Objective Many lacunar stroke patients complained of cognitive decline after stroke. This study aims to investigate the factors underlying post-stroke cognitive complaints in these patients. Methods Seventy-five consecutive lacunar stroke patients without major depression were recruited for the study. Stroke severity was measured using NIHSS score and MRI was performed during the acute admission period. At 3 months, objective psychometric performance and depressive symptoms were assessed. Post-stroke cognitive complaints were corroborated by a proxy. Using logistic regression we examined the contribution of demographic features, stroke severity, objective psychometric scores, depressive symptoms, and imaging features (white matter lesion volume and infarct measures) to post-stroke cognitive complaints. Results Thirty-two (42.7%) patients had post-stroke cognitive complaints. Patients with post-stroke cognitive complaints had more depressive symptoms and worse psychometric performance than those without. In the multivariate logistic regression model, only the severity of depressive symptoms was independently associated with post-stroke cognitive complaints. Conclusions This study suggests that post-stroke cognitive complaints are frequent among lacunar stroke patients without major depression and are prominently determined by the subclinical depressive symptomatology. Copyright © 2010 John Wiley & Sons, Ltd.
- Subjects
CEREBROVASCULAR disease patients; COGNITION disorders; SELF-evaluation; DEPRESSED persons; SYMPTOMS
- Publication
International Journal of Geriatric Psychiatry, 2011, Vol 26, Issue 11, p1144
- ISSN
0885-6230
- Publication type
Article
- DOI
10.1002/gps.2652