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- Title
The role of human T-lymphotropic virus (HTLV) in cardiovascular diseases: A review of literature.
- Authors
Abolbashari, Samaneh; Ghayour-Mobarhan, Majid; Ebrahimi, Mahmoud; Meshkat, Zahra
- Abstract
Cardiovascular diseases are a major cause of morbidity and mortality. Chronic inflammation is an important risk factor for atherosclerosis, and viral infections can cause cardiovascular disease by developing inflammation. Infection with human T-lymphotropic virus (HTLV) is endemic in some parts of the world such as Japan, Africa, Caribbean islands, South America, and Iran. HTLV-1 is an oncogenic retrovirus, and can cause adult T-cell leukemia/lymphoma (ATL or ATLL). It also causes HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). A number of inflammatory diseases such as uveitis, arthritis, and Sjogren's syndrome are also associated with the virus. A few case reports have shown the direct involvement of the heart in HTLV-1-positive patients who develop ATLL. The purpose of this study was to review the literature relevant with the role of HTLV in cardiovascular diseases.
- Subjects
T cells; CARDIOVASCULAR diseases; MORTALITY; LEUKEMIA; RETROVIRUS diseases
- Publication
ARYA Atherosclerosis, 2018, Vol 14, Issue 4, p183
- ISSN
1735-3955
- Publication type
Article
- DOI
10.22122/arya.v14i4.1608