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- Title
Clinical, pathological and immunological aspects of periodontal disease.
- Authors
Kinane, Denis F.; Lappin, David F.; Kinane, D F; Lappin, D F
- Abstract
The inflammatory and immune responses during the development and progression of periodontitis are reviewed. Susceptibility to periodontitis may be related to whether plasma cells predominate in the tissues of an individual, or a site, in response to the microbial insult from dental plaque. The tendency for an individual or site to form an extensive plasma cell infiltrate may indicate an inability to defend against periodontopathogenic bacteria and thus a predisposition to periodontitis. Selected pertinent areas of current interest in cellular and humoral immunology are considered within the periodontal context. These topical issues include (a) homing of immune and inflammatory cells to target tissues; (b) the local proliferation and synthetic activity of immune and inflammatory cells; (c) the cytokine profile of the inflammatory and immune cells; and (d) the immunoglobulin subclasses of locally produced antibodies.
- Subjects
PERIODONTAL disease; IMMUNE response
- Publication
Acta Odontologica Scandinavica, 2001, Vol 59, Issue 3, p154
- ISSN
0001-6357
- Publication type
journal article
- DOI
10.1080/000163501750266747