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- Title
Novel Viral Vector Systems for Gene Therapy.
- Authors
Stone, Daniel
- Abstract
The article presents a study on viral vector systems for gene therapy. It mentions that the most commonly used gene delivery systems were based on adenovirus (Ad), retrovirus, poxvirus, adeno-associated virus (AAV) and herpes simplex virus (HSV) that are cumulatively used in more than 66% of all clinical trials. These viruses are easily manipulated in vitro and have been studied in detail, were gene delivery systems initially developed. It notes that those viral vectors have great attributes which determine their suitability for different therapeutic applications. Moreover, viruses provide the scientific researcher, a tool to develop an understanding of disease and cell biology. Thus, the use of viral vectors for gene therapy could be beneficial in the treatment of many human diseases.
- Subjects
GENETIC vectors; GENE therapy; ADENOVIRUS diseases; VIRAL antibodies; VIRAL antigens; CYTOLOGY; MANAGEMENT of human services; PREVENTIVE medicine; CLINICAL trials; THERAPEUTICS
- Publication
Viruses (1999-4915), 2010, Vol 2, Issue 4, p1002
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v2041002