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- Title
Correlation Analysis between Uric Acid and Metabolic Syndrome in the Chinese Elderly Population: A Cross-Sectional Study.
- Authors
Nie, Guqiao; Wan, Jing jing; Jiang, Lei; Hou, Shu kai; Peng, Wen
- Abstract
Background. Currently, both metabolic syndrome and hyperuricaemia have attracted extensive attention in public health. The correlation between uric acid and metabolic syndrome is controversial. Research on the relationship between uric acid and metabolic syndrome in community-dwelling elderly people is relatively lacking. The purpose of this study is to explore the relationship between uric acid and metabolic syndrome in the community-dwelling elderly people. Design. Cross-sectional study. Methods. We collected the physical examination data of 1,267 elderly people in Gutian community in Wuhan and used SPSS IBM 25.0 for data analysis. Correlation and logistic regression analyses were performed, and ROC curves were drawn. Results. The uric acid level of the nonmetabolic syndrome group was lower than that of the metabolic syndrome group (337.31 vs. 381.91 µmol/L; P < 0.05). Uric acid was positively correlated with systolic blood pressure (r = 0.177, P < 0.001), diastolic blood pressure (r = 0.135, P < 0.001), body mass index (r = 0.234, P < 0.001), waist circumference (r = 0.283, P < 0.001), and triglycerides (r = 0.217, P < 0.05). High-density lipoprotein cholesterol (r = −0.268, P < 0.001) showed the opposite trend. Logistic regression analysis results suggested that uric acid is a risk factor for metabolic syndrome. The result is described as exp (B) and 95% CI (1.003 [1.001, 1.005]). Based on the receiver operating characteristic curve, we found that the area under the curve of uric acid to diagnose metabolic syndrome was 0.64 (sensitivity: 79.3%, specificity: 45.1%). Conclusion. We observed an association between uric acid levels and metabolic syndrome in the elderly Chinese population. The best threshold value for uric acid in predicting metabolic syndrome diagnosis was 314.5 μmol/l.
- Subjects
METABOLIC syndrome risk factors; ANALYSIS of triglycerides; METABOLIC syndrome diagnosis; PHYSICAL diagnosis; RESEARCH; CONFIDENCE intervals; CROSS-sectional method; SYSTOLIC blood pressure; DIASTOLIC blood pressure; INDEPENDENT living; DESCRIPTIVE statistics; WAIST circumference; URIC acid; DATA analysis software; STATISTICAL correlation; LOGISTIC regression analysis; RECEIVER operating characteristic curves; BODY mass index; HIGH density lipoproteins; SENSITIVITY &; specificity (Statistics)
- Publication
International Journal of Endocrinology, 2023, p1
- ISSN
1687-8337
- Publication type
Article
- DOI
10.1155/2023/8080578