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- Title
DESARROLLO Y CRECIMIENTO FEMORAL DE CONEJAS DE LA LÍNEA NEW ZEALAND.
- Authors
CAMAL RUGGIERI, Iván Nadir; RAMALLO, Melina; GRENON, Hernán; MARDEGAN ISSA, Joao Paulo; FELDMAN, Sara
- Abstract
In this project we investigated the changes of femoral development and growth of female New Zealand rabbits (NZr). Animals were maintained in individual cages since they were two weeks old with food and water ad libitum, and were sacrificed monthly consecutively: 1, 2, 3, 4, 5 and 6. Radiological studies were made with femoral pieces to determine femoral neck angle (fnA), total length (L), total bone mineral density (tBMD), bone center mineral density (bcBMD) and femoral metaphysis bone mineral density (fmBMD). We analyzed intergroup variations with Wilcoxon test and Bonferroni correction. We also performed histologic studies with femoral pieces. The fnA analyzes showed a significant increase in the first month while L stabilized since the fourth month. tBMD showed a plateu since the fourth month, even though bcBMD and fmBMD did not show any significant changes since the third month. In histology it was observed the absence of all typical growth cartilage zones since the fourth month, with the only presence of small remaining cartilage cells. In the fifth month we observed complete absence of cartilage, and presence of osteoid tissue only. The integrated interpretation of the results allows us to affirm that since the fourth month of development the femur of NZr acquires characteristics compatible with the adulthood.
- Subjects
FEMUR; FEMUR neck; GROWTH plate; CARTILAGE cells; BONFERRONI correction
- Publication
Acta Biológica Colombiana, 2021, Vol 26, Issue 3, p385
- ISSN
0120-548X
- Publication type
Article
- DOI
10.15446/abc.v26n3.87221