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- Title
Extracorporeal ultrafiltration for acute heart failure: patient selection and perspectives.
- Authors
Milazzo, Valentina; Cosentino, Nicola; Marenzi, Giancarlo
- Abstract
Most patients presenting with acute heart failure (AHF) show signs and symptoms of fluid overload, which are closely associated with short-term and long-term outcomes. Ultrafiltration is an extremely appealing strategy for patients with AHF and concomitant overt fluid overload not fully responsive to diuretic therapy. However, although there are several theoretical beneficial effects associated with ultrafiltration, published reports have shown controversial findings. Differences in selection of the study population and in ultrafiltration indications and protocols, and high variability in the pharmacologic therapy used for the control group could explain some of these conflicting results. Here, we aimed to provide an overview on the current medical evidence supporting the use of ultrafiltration in AHF, with a special focus on the identification of potential candidates who may benefit the most from this therapeutic option.
- Subjects
HEART failure patients; PATIENT selection; MEDICAL protocols; DIURETICS; HEART failure treatment; THERAPEUTICS
- Publication
Vascular Health & Risk Management, 2017, Vol 13, p449
- ISSN
1176-6344
- Publication type
journal article
- DOI
10.2147/VHRM.S128608