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- Title
Cutaneous Leishmaniasis during Pregnancy: Exuberant Lesions and Potential Fetal Complications.
- Authors
Morgan, Daniel J.; Guimaraes, Luiz H.; Machado, Paulo R. L.; D'Oliveira Jr., Argemiro; Almeida, Roque P.; Lago, Ednaldo L.; Faria, Daniela R.; Tafuri, Wagner L.; Dutra, Walderez O.; Carvalho, Edgar M.
- Abstract
Cutaneous leishmaniasis affects millions of people worldwide. After observations of atypical lesions in pregnant women at the health centers of Corte de Pedra, Brazil, 9 years of records were reviewed, and 26 pregnant patients were identified. A retrospective case-control study revealed that lesions in pregnant women were much larger than those in nonpregnant patients in an age- and sex-matched group (mean area, 6.08 cm² vs. 1.46 cm²;P = .008), and many lesions had an exophytic nature. Despite foregoing treatment until after delivery, response to pentavalent antimony therapy was favorable (rate of cure with 1 course of treatment, 85%). High rates of preterm births (10.5%) and stillbirths (10.5%) were reported. Cutaneous leishmaniasis during pregnancy produces distinct lesions and may have adverse fetal effects.
- Subjects
BRAZIL; LEISHMANIASIS; PREGNANCY complications; PREGNANT women; MEDICAL care; FETAL death
- Publication
Clinical Infectious Diseases, 2007, Vol 45, Issue 4, p478
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1086/520017