We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Seroprevalence of Norwalk Virus and Mexico Virus in Chilean Individuals: Assessment of Independent Risk Factors for Antibody Acquisition.
- Authors
O'Ryan, Miguel L.; Víal, Pablo A.; Mamani, Nora; Jiang, Xi; Estes, Mary K.; Ferrecio, Catterine; Lakkis, Hassan; Matson, David O.
- Abstract
Norwalk virus (NV) and Mexico (MX) virus represent distinct genetic clusters within the same genus of human caliciviruses (CVs), a major cause of diarrhea in adults. The magnitude and potential risk factors of human CV infection in populations from Santiago and Punta Arenas, Chile, were assessed. Individuals (n = 1,864) gave a blood sample and answered a questionnaire during a household survey. Sera were tested for antibody to NV and MX virus with use of recombinant capsid antigens. Overall, NV and MX virus seroprevalence rates were 83% and 91% in Santiago vs. 67% and 90% in Punta Arenas, respectively (P < .001 for NV virus). Lower socioeconomic status and increasing age were risk factors for infection with both viruses (P < .001). Consumption of seafood, consumption of vegetables, and child care center attendance were population risk factors for infection, but the association of a factor with a virus depended on the city. Prevention of human CV infections will require individual assessment in different communities.
- Publication
Clinical Infectious Diseases, 1998, Vol 27, Issue 4, p789
- ISSN
1058-4838
- Publication type
Article