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- Title
Effect of epidural morphine on the Hoffman-reflex in man.
- Authors
Grossi, P.; Arnér, S.; Arnér, S
- Abstract
Four healthy, young subjects undergoing knee surgery with epidural anaesthesia were given epidural morphine for the relief of post-surgical pain. The Hoffman (H)-reflex was tested before and after the injection of morphine in the epidural space. The reflex was chosen as a monitor of the function of monosynaptic pathways in the spinal cord. Analogue scales for the measurement of pain revealed a satisfactory decrease of nociception after morphine injection, while the H-reflex was not significantly affected. This study may confirm that monosynaptic reflexes are not affected by epidural administration of morphine and that they are probably not involved in pain transmission.
- Subjects
INJECTIONS; REFLEXES; MORPHINE; EPIDURAL space; H-reflex; POSTOPERATIVE pain; PHARMACODYNAMICS
- Publication
Acta Anaesthesiologica Scandinavica, 1984, Vol 28, Issue 2, p152
- ISSN
0001-5172
- Publication type
journal article
- DOI
10.1111/j.1399-6576.1984.tb02032.x