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- Title
Nebulized heparin for burned patients with inhalation injury: a review.
- Authors
Neagu, Tiberiu Paul; Tiglis, Mirela; Sebe, Ioana Teona; Raducu, Laura; Lascar, Ioan
- Abstract
The presence of inhalation injury has a negative impact on the evolution of burned patients, being associated with increased mortality. It occurs as a direct consequence of thermal action, or secondary to the presence of respiratory irritants or absorption of toxins, and actual therapeutic management is mainly supportive. Several clinical findings are relevant to raising suspicion and guiding further examinations, fiberoptic bronchoscopy being the gold standard of diagnosis and staging. In burned patients with inhalation injuries, various reports showed that nebulized heparin (5,000 or 10,000 units) with a 4-hour administration regimen leads to improved outcome, reduces the days of mechanical ventilation and consequently the length of hospital stay, reduces pulmonary complications and improves lung function, having a safe profile, with fewer side effects.
- Subjects
INHALATION injuries; HEPARIN; MUSTARD gas; LENGTH of stay in hospitals; TOXINS; ARTIFICIAL respiration
- Publication
Romanian Medical Journal, 2022, Vol 69, Issue 1, p5
- ISSN
1220-5478
- Publication type
Article
- DOI
10.37897/RMJ.2022.1.1