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- Title
Nomogram of peripapillary retinal nerve fiber layer thickness in myopic eyes of north Indian population.
- Authors
Yasir, Ziaul; Mittal, Jimmy; Singh, Alok; Yasir, Ziaul H; Singh, Alok K
- Abstract
<bold>Purpose: </bold>To evaluate peripapillary-RNFL thickness in myopia by Cirrus OCT among north Indian population by spherical equivalent (SE), age, gender, and axial length (AL).<bold>Methods: </bold>This was a cross-sectional study held during 2019-2020. Patients aged 18-60 years underwent ophthalmic examination including retinoscopy, AL, and OCT RNFL thickness. Persons with previous ocular surgery or ocular ailment other than refractive error were excluded. The peripapillary-RNFL thickness was noted and compared by demographic determinants.<bold>Results: </bold>We examined 300 eyes of 300 persons (mean age: 30.75 ± 8.57 years; 144 males/156 females). Among them, 224 were myopes and 76 were emmetropes (EM). The mean SE was - 3.3 ± 0.4D (range: -11.0D to + 0.37D). The mean AL was 24.61 ± 1.92 mm (22.1-29.5). Overall temporal, nasal, superior, inferior, and mean peripapillary-RNFL thickness was 66.31 ± 7.58, 78.57 ± 16.00, 120.63 ± 11.69, 116.60 ± 15.80, and 95.50 ± 10.84 μm, respectively. Temporal, nasal, superior, inferior, and mean peripapillary-RNFL thickness was 73.97 ± 8.36, 94.84 ± 7.63, 127.96 ± 8.96, 136.89 ± 6.53, and 108.34 ± 6.28 μm, respectively, in EM eyes as compared to 63.71 ± 6.18, 73.05 ± 14.24, 118.21 ± 11.53, 109.71 ± 11.50, and 91.14 ± 8.31 μm, respectively, in myopic eyes (P < 0.001). Association of peripapillary-RNFL thickness with myopia and its different grades was P < 0.001. Association of mean peripapillary-RNFL thickness with age was P > 0.005 and gender was P = 0.168. Correlation between SE and RNFL thickness was positive and significant. Correlation between AL and RNFL thickness was negative but statistically significant. Association of AL with SE was P < 0.001.<bold>Conclusion: </bold>We provide normative peripapillary-RNFL thickness in the north Indian population in order to help in screening for myopia with comorbidity such as glaucoma based on RNFL thickness.
- Subjects
NERVE fibers; NOMOGRAPHY (Mathematics); REFRACTIVE errors; MYOPIA; RETINOSCOPY; CROSS-sectional method; LASIK; PHOTOREFRACTIVE keratectomy; RETINA; NEURONS; OPTICAL coherence tomography; STATISTICAL models; DISEASE complications
- Publication
Indian Journal of Ophthalmology, 2022, Vol 70, Issue 2, p458
- ISSN
0301-4738
- Publication type
journal article
- DOI
10.4103/ijo.IJO_767_21