We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Current status of head and neck sarcomas in Japan in 2016–2019: an analysis using the national cancer registry.
- Authors
Rikitake, Ryoko; Mizushima, Yu; Yoshimoto, Seiichi; Higashi, Takahiro; Satake, Tomoyuki; Morizane, Chigusa; Kawai, Akira
- Abstract
Background: Head and neck sarcomas are especially rare in Asia, leading to limited clinical evidence. This study aimed to investigate the incidence, clinical features, treatment status, and outcome of these sarcomas using data from the National Cancer Registry in Japan. Methods: All head and neck sarcomas diagnosed between 2016 and 2019 and recorded in the National Cancer Registry were analyzed. Data on sex, age, primary site, histological type, stage, treatment modality, and prognostic information were collected. Age-adjusted incidence and 3-year survival rates of patients with head and neck sarcomas were calculated. Results: Overall, 635 head and neck sarcoma patients were identified. Head and neck sarcoma occurred more frequently in men and patients in their 70 s. The age-adjusted annual incidence rate was 0.125 per 100,000 patients in the 2015 Japanese model or 0.089 per 100,000 patients in the world population model. The nasal cavity and paranasal sinuses were the most frequent primary sites, with rhabdomyosarcoma as the most common histologic type. Treatment typically involved chemotherapy and/or radiation therapy for rhabdomyosarcoma and Ewing's sarcoma, whereas surgical approaches for other types. Three-year survival rate of head and neck sarcoma patients was 64.8%. Conclusions: Head and neck sarcomas occurred rarely, but most frequently in the nasal cavity and paranasal sinuses in Japan. Poor outcomes were observed for sarcoma patients than for non-sarcoma head and neck cancer patients.
- Subjects
JAPAN; HEAD &; neck cancer; EWING'S sarcoma; SARCOMA; PARANASAL sinuses; NASAL cavity; NECK
- Publication
International Journal of Clinical Oncology, 2024, Vol 29, Issue 5, p564
- ISSN
1341-9625
- Publication type
Article
- DOI
10.1007/s10147-024-02484-5