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- Title
Ergonovine-Induced Changes of Coronary Artery Diameter in Patients with Nonsignificant Coronary Artery Stenosis.
- Authors
Milan Nedeljkovic; Branko Beleslin; Ivana Nedeljkovic; Natasa Milic; Vladan Vukcevic; Sinisa Stojkovic; Jovica Saponjski; Dejan Orlic; Ana Djordjevic-Dikic; Jelena Stepanovic; Vojislav Giga; Zorica Petrasinovic; Aleksandra Arandjelovic; Biljana Beleslin; Vladimir Kanjuh
- Abstract
Abstract Background and Purpose: Serum cholesterol is positively associated with the risk of developing coronary heart disease. The aim of this study was to determine the relation between response of coronary arteries to ergonovine provocation and lipid profile in patients with nonsignificant coronary artery disease. Patients and Methods: 105 patients (46 male, 59 female, mean age 52 8 years) with chest pain syndrome and nonsignificant coronary artery stenosis ( Results: There was a significant negative correlation between resting MLD and LDL cholesterol (r = –0.215; p = 0.034), and a significant positive correlation between MLD decrease provoked by ergonovine and total cholesterol (r = 0.275; p = 0.006), as well as LDL cholesterol (r = 0.284; p = 0.004), but not for HDL cholesterol and triglycerides (p = NS [not significant]). Conclusion: In patients with nonsignificant coronary artery stenosis evaluated by ergonovine provocation, there was not only a significant negative correlation between MLD and LDL cholesterol, but also a positive correlation between coronary vasoconstriction induced by ergonovine provocation and both total and LDL cholesterol.
- Subjects
BLOOD cholesterol; CORONARY disease; CORONARY artery stenosis; TRIGLYCERIDES; VASOCONSTRICTION; RESEARCH
- Publication
Herz, 2007, Vol 32, Issue 4, p329
- ISSN
0340-9937
- Publication type
Article
- DOI
10.1007/s00059-007-2831-4