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- Title
Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats.
- Authors
Haiming Zhu; Liang Ding; Haijun Xiao; Weifeng Ni; Feng Xue; Zhiming He
- Abstract
Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats.
- Subjects
LABORATORY rats; BIOACTIVE compounds; PHYTOCHEMICALS; LIU wei di huang; PARATHYROID hormone; CALCITONIN
- Publication
Molecules, 2012, Vol 17, Issue 7, p8001
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules17078001