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- Title
Use of mycophenolate mofetil in refractory relapsing polychondritis.
- Authors
Borowy, Przemysław; Smyk, Jakub; Major, Patrycja; Mglej, Natalia; Batko, Bogdan
- Abstract
Relapsing polychondritis (RP) remains a difficult-totreat disease of unknown aetiology and uncertain prognosis. Based on McAdam's criteria, rheumatoid arthritis (RA) was diagnosed in a 51-year-old female patient, and sequential therapy with dapsone -- followed by naproxen and methylprednisolone -- was initiated without achieving full remission. During the following years, the patient developed new locations of polychondritis (nose, epiphyses of long bones) and episcleritis. Methotrexate (MTX) was started, which was changed to mycophenolate mofetil (MM) due to adverse effects, resulting in sustained clinical improvement. There were no relapses during the subsequent 12 months of follow-up. The use of MM with good therapeutic effect in our patient is one of the few reported cases of such therapy in a patient with RP.
- Subjects
MYCOPHENOLIC acid; CARTILAGE diseases; METHYLPREDNISOLONE; NAPROXEN; DISEASE remission
- Publication
Rheumatology Forum, 2024, Vol 10, Issue 1, p43
- ISSN
2720-3921
- Publication type
Article
- DOI
10.5603/rf.97201