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- Title
Olfactory bulbectomy leads to prolonged induction phase of sevoflurane anesthesia in rats.
- Authors
Ahiskalioglu, Ali; Kanat, Ayhan; Aydin, Mehmet; Kazdal, Hizir; Kocak, Nuri; Ozmen, Sevilay
- Abstract
The effect of olfactory bulb lesions on the induction time of sevoflurane has never been studied. We aimed to investigate this issue. In this study, we found that the volume of olfactory bulbs and the pore of the fila olfactoria were significantly lower with the fibrosis of olfactory bulbs in animals subjected to olfactory bulbectomy. Volatile anesthetics induction times were measured in all groups. Prolonged induction was observed in olfactory bulbectomy group. It was concluded that increased induction times of sevoflurane may be due to the olfactory bulb lesion.
- Subjects
OLFACTORY bulb; SEVOFLURANE; RATS; ANESTHESIA
- Publication
Medical Gas Research, 2024, Vol 14, Issue 1, p33
- ISSN
2045-9912
- Publication type
Article
- DOI
10.4103/2045-9912.378881