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- Title
Tyr-c[D-Orn-Tyr(Bzl)-Pro-Gly]: a novel antiproliferative acting somatostatin receptor agonist with µ-opioid receptor-sensitizing properties.
- Authors
Stirnweiss, Jorg; Hartrodt, Bianka; Greksch, Gisela; Sturzebecher, Uta; Bohmer, Frank-D.; Neubert, Klaus; Liebmann, Claus
- Abstract
Discusses beta-casomorphin-5-derived cyclic pentapeptide, cyclic casomorphin derivative-2 (cCD-2) which inhibits the cell growth of a variety of human cancer cell lines. Antiproliferative effect of cCD-2; Role of cCD-2 in stimulating the activity of protein tyrosine phosphatases; Difference from somatostatin receptor agonists.
- Subjects
SOMATOSTATIN; PEPTIDE hormones; DRUG receptors
- Publication
British Journal of Pharmacology, 2003, Vol 140, Issue 1, p13
- ISSN
0007-1188
- Publication type
Article
- DOI
10.1038/sj.bjp.0705416