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Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99401-x
By:
- Schardt, John S.;
- Pornnoppadol, Ghasidit;
- Desai, Alec A.;
- Park, Kyung Soo;
- Zupancic, Jennifer M.;
- Makowski, Emily K.;
- Smith, Matthew D.;
- Chen, Hongwei;
- Garcia de Mattos Barbosa, Mayara;
- Cascalho, Marilia;
- Lanigan, Thomas M.;
- Moon, James J.;
- Tessier, Peter M.
Publication type:
Article
Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31457-3
By:
- Makowski, Emily K.;
- Kinnunen, Patrick C.;
- Huang, Jie;
- Wu, Lina;
- Smith, Matthew D.;
- Wang, Tiexin;
- Desai, Alec A.;
- Streu, Craig N.;
- Zhang, Yulei;
- Zupancic, Jennifer M.;
- Schardt, John S.;
- Linderman, Jennifer J.;
- Tessier, Peter M.
Publication type:
Article
Development of a pan‐tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates.
Published in:
Biotechnology Progress, 2024, v. 40, n. 5, p. 1, doi. 10.1002/btpr.3463
By:
- McArthur, Nikki;
- Kang, Bokyung;
- Rivera Moctezuma, Felix G.;
- Shaikh, Akber T.;
- Loeffler, Kathryn;
- Bhatt, Nemil N.;
- Kidd, Madison;
- Zupancic, Jennifer M.;
- Desai, Alec A.;
- Djeddar, Naima;
- Bryksin, Anton;
- Tessier, Peter M.;
- Kayed, Rakez;
- Wood, Levi B.;
- Kane, Ravi S.
Publication type:
Article
Directed evolution of conformation‐specific antibodies for sensitive detection of polypeptide aggregates in therapeutic drug formulations.
Published in:
Biotechnology & Bioengineering, 2021, v. 118, n. 2, p. 797, doi. 10.1002/bit.27610
By:
- Lou, Wenjia;
- Stimple, Samuel D.;
- Desai, Alec A.;
- Makowski, Emily K.;
- Kalyoncu, Sibel;
- Mogensen, Jesper E.;
- Spang, Lotte T.;
- Asgreen, Désirée J.;
- Staby, Arne;
- Duus, Karen;
- Amstrup, Jan;
- Zhang, Yulei;
- Tessier, Peter M.
Publication type:
Article
Sensitive detection of glucagon aggregation using amyloid fibril‐specific antibodies.
Published in:
Biotechnology & Bioengineering, 2019, v. 116, n. 8, p. 1868, doi. 10.1002/bit.26994
By:
- Stimple, Samuel D.;
- Kalyoncu, Sibel;
- Desai, Alec A.;
- Mogensen, Jesper E.;
- Spang, Lotte T.;
- Asgreen, Désirée J.;
- Staby, Arne;
- Tessier, Peter M.
Publication type:
Article
A hybridoma-derived monoclonal antibody with high homology to the aberrant myeloma light chain.
Published in:
PLoS ONE, 2021, v. 16, n. 10, p. 1, doi. 10.1371/journal.pone.0252558
By:
- Pornnoppadol, Ghasidit;
- Zhang, Boya;
- Desai, Alec A.;
- Berardi, Anthony;
- Remmer, Henriette A.;
- Tessier, Peter M.;
- Greineder, Colin F.
Publication type:
Article
Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants.
Published in:
Advanced Therapeutics, 2021, v. 4, n. 8, p. 1, doi. 10.1002/adtp.202100099
By:
- Zupancic, Jennifer M.;
- Schardt, John S.;
- Desai, Alec A.;
- Makowski, Emily K.;
- Smith, Matthew D.;
- Pornnoppadol, Ghasidit;
- Garcia de Mattos Barbosa, Mayara;
- Cascalho, Marilia;
- Lanigan, Thomas M.;
- Tessier, Peter M.
Publication type:
Article
Affinity targeting of therapeutic proteins to the bone surface—local delivery of sclerostin–neutralizing antibody enhances efficacy.
Published in:
Journal of Bone & Mineral Research, 2024, v. 39, n. 6, p. 717, doi. 10.1093/jbmr/zjae050
By:
- Zhang, Boya;
- Swanson, William Benton;
- Durdan, Margaret;
- Livingston, Heather N;
- Dodd, Michaela;
- Vidanapathirana, Sachith M;
- Desai, Alec;
- Douglas, Lindsey;
- Mishina, Yuji;
- Weivoda, Megan;
- Greineder, Colin F
Publication type:
Article
Native ion mobility‐mass spectrometry reveals the binding mechanisms of anti‐amyloid therapeutic antibodies.
Published in:
Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 6, p. 1, doi. 10.1002/pro.5008
By:
- Han, Yilin;
- Desai, Alec A.;
- Zupancic, Jennifer M.;
- Smith, Matthew D.;
- Tessier, Peter M.;
- Ruotolo, Brandon T.
Publication type:
Article

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